In one person with Parkinson’s disease, freezing of gait was averted through the use of a soft robotic apparel that provided a moderate level of hip-flexion assistance during the swing phase of walking. This approach delivered instantaneous effects and consistently improved walking quality and function across a range of conditions.
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References
Lewis, S. et al. Stepping up to meet the challenge of freezing of gait in Parkinson’s disease. Transl. Neurodegener. 11, 23 (2022). This perspective discusses gaps and shortcomings in the FoG field, including the standardization of definitions and measurement, phenomenology and pathophysiology.
Kim, J. et al. Reducing the energy cost of walking with low assistance levels through optimized hip flexion assistance from a soft exosuit. Sci. Rep. 12, 11004 (2022). This paper shows a soft wearable robot to augment walking and running in healthy people.
Plotnik, M., Giladi, N. & Hausdorff, J. M. Is freezing of gait in Parkinson’s disease a result of multiple gait impairments? Implications for treatment. Parkinsons Dis. 2012, 459321 (2012). This paper introduces the concept that more than one gait-control mechanism (that is, deteriorations in rhythm control, coordination of gait, and step scaling) might be impaired in FoG, and that these mechanisms may interact to trigger a FoG episode.
Ahn, J. & Hogan, N. Walking is not like reaching: evidence from periodic mechanical perturbations. PLoS ONE 7, e31767 (2012). This paper demonstrates that healthy people can adjust their step frequency to that of pulses delivered by an ankle exoskeleton.
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This is a summary of: Kim, J. et al. Soft robotic apparel to avert freezing of gait in Parkinson’s disease. Nat. Med. https://doi.org/10.1038/s41591-023-02731-8 (2024).
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Wearable robot helps man with Parkinson’s disease to walk. Nat Med 30, 47–48 (2024). https://doi.org/10.1038/s41591-023-02756-z
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DOI: https://doi.org/10.1038/s41591-023-02756-z